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Metabolism Resmetirom is metabolized by CYP2C8 and isn't metabolized by other CYP enzymes in vitro. MGL-3623 is a major metabolite using a 28-times lessen potency for THR-β than resmetirom.Ailment-Linked Maternal and/or Embryo/Fetal Risk There are actually dangers towards the mother and fetus associated with underlying maternal NASH with liver fib